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KMID : 0363819940280010157
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Korean Journal of Nuclear Medicine
1994 Volume.28 No. 1 p.157 ~ p.158
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Focal Nodular Hyperplasia Diagnosed by ^(99m)Tc-Phytate Liver SPECT
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Ryu, Jin-Sook
Moon, Dae Hyuk/Shin, Seong Hae
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Abstract
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A 17-year-old female was referred to department of nuclear medicine for the evaluation of a 4 X 5 cm sized hypoechoic hepatic mass on ultrasonopaphy (Fig 1). She had no history of taking oral contraceptives.
Rhysical examination and laboratory findings were normal. Abdominal CT demonstrated circumscribed homogeneous low density mass without a ,,central scar (Fig. 2).
Tc99m RBC SPECT of liver showed normal blood spooling within mass (Fig. 3). Tc-99m phytate liver ;scintigraphy was performed to evaluate radiocolloid uptake in liver. Tc-99m phytate planar scintigraphy was normal (Fig. 4), however SPECT revealed round p ncreased tracer accumulation on the corresponding lesion (Fig. 5).
F he differential diagnosis of solitary solid hepatic mass is relatively common clinical challenge. If the clinical ´and radiological data suggest either adenoma or focal nodular hyperplasia (FNH), a radiocolloid scan is a logical next step. Pathologically FNH consists of randomly organized collection of
3 hepatocytes, Kupffer cells, fibrous septae, and bile ducts. FNH takes up sulfur colloid and appears
either hot or normal on liver scan in 65-70% of cases. Increased concentration of the radiopharmaceutical is considered as a pathognomic finding of FNH and SPECT can provide further information on the nature of the lesion.
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